What is Cool Laser Therapy?

Theralase® patented cool laser therapy ("CLT") devices are clinically indicated and cleared by global regulatory bodies for the treatment of chronic knee pain, and in off-label use, the elimination of pain, reduction of inflammation, and dramatic acceleration of tissue healing for numerous nerve, muscle, and joint conditions. Our customers receive one of the most advanced therapeutic laser technology on the market, supported by interactive training, and the most up-to-date clinical protocols to ensure the success of their practice.

Cellular Pathway Activation

Theralase® utilizes dual wavelength super pulsing technology (660 nm visible red laser diodes and 905 nm super-pulsed near infrared laser diodes) to activate all three known cellular pathways simultaneously. Light from laser penetrates into tissue, where light energy is converted into chemical or physical energy. 

Eliminates Pain (+)

Theralase®  laser technology effectively removes the pain signal at the source by rebalancing the sodium potassium pathway.

Pain results when a stimulus causes action potentials to rapidly propagate along a nerve cell. Actions potentials are mostly due to an influx of sodium ions into the nerve cell and potassium ions out of the cell, altering the electrical potential across the membrane. The 905nm light activates receptors within the membrane leading to increased porosity of the membrane and altering the flow of sodium and potassium ions. The opening of these channels allows flow of Na+ ions back out and K+ ions back in, helping to rebalance ion levels and restore a resting state in the cell. This change in electron gradient across a nerve cell can stop the propagation of impulses across the cell and remove pain signals at the source.

Peak Activation By 905 nm
Near Infrared Red Light

Lipid Absorption 


Reduces Inflammation (+)

Independent research proves that the proprietary Theralase®  905nm superpulsed laser technology increases the production of Nitric Oxide (NO) by over 700%, increasing vasodilation and decreasing inflammation versus other competitive wavelengths.

The inner lining of blood vessels uses NO to signal the surrounding smooth muscle to relax, thus resulting in vasodilation and increased blood flow (and thereby, increased oxygen supply) to the area. This ultimately results in decreased inflammation and edema. Furthermore, increasing blood flow to injured tissue will accelerate the body’s natural healing process, deliver nutrient-rich blood and oxygen to the injury site and eliminate toxins or waste by-products created during the inflammatory process.

Activated By 905 nm
Near Infrared Red Light

Nitric Oxide

(NO) Pathway

Accelerates Healing (+)

Theralase®  stimulates the mitochondria of the cell to produce more Adenosine Triphosphate (ATP or basic cell energy) to accelerate tissue repair. 

Laser light is absorbed in the mitochondria of the cell, specifically by cytochrome c oxidase within the respiratory chain, leading to the release of ATP (energy) and nitric oxide (NO) and the modulation of reactive oxygen species (ROS). Mitochondria in stressed or ischemic tissues produce nitric oxide (mtNO) that binds to cytochrome c oxidase competitively displacing oxygen and leading to oxidative stress and reduced ATP production. Light, when applied to injuries, is absorbed by cytochrome c oxidase displacing mitochondrial NO and thereby reducing oxidative stress and increasing ATP production. From there, a cascade of downstream metabolic effects lead to a reduction in inflammatory markers and accelerate tissue repair.

630 to 670 nm
Visible Red Light peaking at 660 nm

Adenosine Triphosphate

(ATP) Pathway

The superpulsed 905 nm technology allows for the delivery of light to deeper target tissues. High peak power (100 W) laser diodes delivered in bursts of very short duration (200 nanoseconds) at high frequencies (10 kHz) provide a high number of photons without causing tissue heating at the surface.

TLC-2000 delivers energy up to 5" deep into tissue

To be effective, laser therapy devices must:

(a) generate light of the correct wavelength

(b) penetrate tissue to the required depth

(c) deliver the required dose of light to the tissue of interest

(d) stimulate a biological response

However, every patient is different. Each treatment needs to be customized for every patient to ensure that they are receiving the optimal dosage of laser energy.

Additional Benefits of Cool Laser Therapy

Safe (+)

Unlike Class 4 laser systems, Theralase® technology does not generate heat and therefore does not pose a risk of damaging or burning tissue. Theralase® laser systems are pain-free, drug-free, non-toxic, and non-invasive, with no known side effects or discomfort to patients.

Return on Investment (ROI) (+)

Everyone benefits from using the Theralase® laser system; your patient gets better through safe and effective treatments, while your practice generates increased revenue. 

Effective (+)

Theralase® treatments often generate immediate results and routinely produce efficacy rates of over 90%. More than 5,000 clinical studies have demonstrated the efficacy of low-level laser therapy.

View our collection of Clinical Studies here

Reimbursement in USA (+)

Theralase® is more affordable than ever for US practitioners and patients. With Current Procedural Terminology (CPT) codes assigned by the American Medical Association, the Theralase® reimbursement strategy allows practitioners and patients to claim cold laser treatments through public health insurance programs, as well as private programs.

A Powerful Alternative for Pain Medication (+)

Theralase® cool laser treatments are a safe and effective alternative to oral analgesics (including Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) and acetaminophen/Tylenol), corticosteroid injections, opiate pain medications, and surgery. Drug-free and pain-free, Theralase® treatments minimize recovery times without any known side effects or discomfort to patients.

Public Reimbursement in USA (+)

Theralase® treatments are reimbursable through public insurance in the United States Average cost per treatment with public reimbursement is between $0 and $40. The total level of reimbursement is dependant on third party insurer and state.

Partnering to Grow Your Practice

In addition to providing you our latest cutting-edge technology, Theralase® will partner with you to help you deliver superior treatment outcomes for your patients and grow your business.

   Training for all clinic staff

   Technical support by Internet remote access

   Full coverage product warranty

   Software updates and upgrades

   Updates to programmed treatment protocols based on actual treatment data derived from Theralase® systems worldwide