Toronto, Ontario – January 15th, 2024, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV:TLT) (OTCQB:TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses is providing an update regarding its Phase II Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study II”). To date, Study II has provided the primary study treatment for 63 patients. In 2016, Kamat et al. stated in the Journal of Clinical Oncology that the International Bladder Cancer Group (“IBCG”) recommended that, “Single-arm designs may be relevant for the BCG-unresponsive population. Here, a clinically meaningful initial complete response rate (for carcinoma in situ) or recurrence-free rate (for papillary tumors) of at least 50% at 6 months, 30% at 12 months and 25% at 18 months is recommended.”[1] Based on the 63 patients treated to … Read More
Theralase Release’s 3Q2023 Interim Financial Statements
Toronto, Ontario – November 29th, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses has released the Company’s 3Q2023 unaudited condensed interim consolidated Financial Statements (“Financial Statements”). Financial Summary: For the nine-month period ended September 30th: 1 Other represents foreign exchange, interest accretion on lease liabilities and / or interest income Financial Highlights for the Nine-Month Period Ended September 30th, 2023: Total revenue decreased 13%, year over year. Cost of sales for the nine-month period ended September 30th, 2023 was $363,882 or 51% of revenue resulting in a gross margin of $342,813 or 49% of revenue. In comparison, the cost of sales for the same period in 2022 was $389,232 or 48% of revenue resulting … Read More
Theralase® Announces Brokered LIFE Financing
Toronto, Ontario – October 23, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses. Theralase® is pleased to announce that it has entered into an agreement with Research Capital Corporation as the sole agent and sole bookrunner (“RCC” or “Agent”) on a “best efforts” agency basis, brokered offering (“Offering”) of units of the Company (“Units”) at a price of C$0.22 per Unit. The Offering will be subject to a minimum of 15,909,091 Units and a maximum of 24,090,910 Units at a price of C$0.22 per Unit for aggregate gross proceeds to the Company of a minimum C$3,500,000 and up to a maximum of C$5,300,000. Each Unit consists of one (1) common share of the Company (“Common Share”) and one (1) Common Share purchase warrant (“Warrant”). Each Warrant will entitle … Read More
Theralase® Provides Update on Bladder Cancer Clinical Study
Theralase®’s Latest Clinical Data Demonstrates 65% of Patients Treated with Theralase®’s Anti-Cancer Therapy Achieved a Complete Response Toronto, Ontario – October 16, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF) is a clinical stage pharmaceutical company dedicated to the research and development of light or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses. Theralase® is providing an update to its Phase II Bacillus Calmette Guérin (“BCG”)-Unresponsive Non-Muscle Invasive Bladder Cancer (“NMIBC”) Carcinoma In-Situ (“CIS”) (with or without resected Ta / T1 papillary disease) clinical study (“Study II”). To date, Theralase® has enrolled and provided the primary Study II Treatment for 62 patients. The Study II Endpoints have been defined as: Primary: Efficacy – Defined as Complete Response (“CR”) rate at any point in time (CR is defined as at least one of the following: Secondary: Duration of CR – Defined as 12 months post initial CR assessment Tertiary: Safety … Read More
Theralase® Successfully Completes Non-GLP Toxicity Analysis for Brain Cancer
Toronto, Ontario – September 27, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF) is a clinical stage pharmaceutical company that is dedicated to the research and development of light and radiation activated Photo Dynamic Compounds (“PDCs”), their associated drug formulations and the light systems that activate them. These PDCs are intended to safely and effectively destroy various cancers, bacteria and viruses when light or radiation activated. Theralase® announced that it has successfully completed its non-Good Laboratory Practices (“GLP”) preclinical toxicology analysis of Rutherrin® for Glio Blastoma Multiforme (“GBM”). GBM is the most aggressive and most common type of brain cancer. The preclinical toxicology data collected to date has demonstrated that Theralase®’s Rutherrin® (RuvidarTM + human transferrin) PDC is able to be safely administered Intra Venously (“IV”) into brain cancer animal models and then successfully hunt, target and significantly accumulate inside GBM cells versus healthy brain cells. When the PDC is activated by radiation … Read More
Theralase Release’s 2Q2023 Interim Financial Statements
Toronto, Ontario – August 29th, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”), their associated drug formulations and the light systems that activate them, intended to safely and effectively destroy various cancers has released the Company’s 2Q2023 unaudited condensed interim consolidated Financial Statements (“Financial Statements”). Financial Summary: For the six-month period ended June 30th: Audited Consolidated Statements of Operations(In Canadian Dollars) 2023 2022 % Change Revenue Canada 305,666 426,990 -28% United States 120,421 125,452 -4% Total Revenue 426,087 552,442 -23% Cost of Sales 224,947 271,656 -17% Gross Margin 201,140 280,786 -28% Gross Margin (% of revenue) 47% 51% Operating Expenses Selling Expenses 147,304 167,139 -12% Administrative Expenses 1,010,144 734,081 38% Research and Development Expenses – Device Division 25,163 105,353 -76% … Read More
Theralase® Announces Appointment of New Independent Director
Toronto, Ontario – June 6, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company focused on the research and development of light-activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations, used to safely and effectively destroy various cancers, bacteria and viruses, is pleased to announce the appointment of new independent director, Kaouthar Lbiati, M.D., M.Sc. Dr. Lbiati received her Doctor of Medicine from Rabat, Morocco’s Mohammed V University and a post-doctorate in clinical oncology from Gustave Roussy Institute in Paris, which is a premier European cancer center and one of the five most prominent cancer centers in the world. She holds a specialized executive master’s degree in strategy and management from ESSEC Business School in Paris, a master’s degree in international policy and health economics from the London School of Economics, a corporate governance certification from Columbia Business School and finance … Read More
Theralase® Releases Corrected and Restated Press Release for 1Q2023 Interim Financial Statements
In the Performance to Primary, Secondary and Tertiary Objectives second table the 90 day results were misstated and has been corrected in this press release. Toronto, Ontario – May 30 2023, Theralase® Technologies Inc. (“Theralase” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations intended to safely and effectively destroy various cancers has released the Company’s 1Q2023 unaudited condensed interim consolidated Financial Statements (“Financial Statements”). Financial Summary: For the three-month period ended March 31st: Audited Consolidated Statements of Operations (In Canadian Dollars) 2023 2022 % Change Revenue Canada 152,174 179,145 -15% United States 55,037 32,517 69% Total Revenue 207,161 211,662 -2% Cost of Sales 114,638 120,430 -4% Gross Margin 92,523 91,232 1% Gross Margin (% of revenue) 45% 43% Operating Expenses Selling Expenses … Read More
Theralase® Appoints Roger DuMoulin-White as President and Chief Executive Officer
Toronto, Ontario – May 24, 2023,Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company focused on the research and development of light-activated Photo Dynamic Compounds (“PDCs”) and their associated drug formulations, used to safely and effectively destroy various cancers, bacteria and viruses, is pleased to announce that Roger DuMoulin-White, B.Sc., P.Eng., Pro. Dir. has been appointed as President and Chief Executive Officer (“CEO”) of the Company. Dr. Arkady Mandel, MD, PhD, DSc has tendered his resignation as Interim CEO, but will continue to serve as Chief Scientific Officer (“CSO”) and as a member of Theralase®’s Board. Mr. DuMoulin-White is the founder of Theralase® and it’s former President and CEO. He stepped down as President and CEO in 2018 and has since served in a non-executive business development role. Mr. DuMoulin-White was the subject of a voluntary Settlement Agreement with the Ontario Securities Commission (“OSC”) dated February … Read More
Theralase® Provides Update on Phase II Bladder Cancer Study
For the primary objective, 65% of Evaluable Patients (Patients evaluated by a Principal Investigator (“PI”)) achieved a Complete Response (“CR”) at any assessment date post primary Study Treatment and 30% of Evaluable Patients achieved a CR at 450 days. Toronto, May 10, 2023 (ACCESWIRE) – Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company focused on the research and development of light activated Photo Dynamic Compounds (“ PDCs”) and their associated drug formulations, used to safely and effectively destroy various cancers, bacteria and viruses, announced today an update on its recently reported Phase II clinical study (“Study II”) interim clinical data. Background: Study II was designed to treat patients diagnosed with Bacillus Calmette-Guérin (“BCG”)-Unresponsive, Non-Muscle Invasive Bladder Cancer (“NMIBC”) Carcinoma In-Situ (“CIS”) (with or without resected papillary Ta/T1 disease) with a patented investigational study drug Ruvidar™ (TLD-1433 – a ruthenium based PDC intravesically instilled … Read More