Toronto, Ontario – January 15th, 2024, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV:TLT) (OTCQB:TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses is providing an update regarding its Phase II Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study II”). To date, Study II has provided the primary study treatment for 63 patients. In 2016, Kamat et al. stated in the Journal of Clinical Oncology that the International Bladder Cancer Group (“IBCG”) recommended that, “Single-arm designs may be relevant for the BCG-unresponsive population. Here, a clinically meaningful initial complete response rate (for carcinoma in situ) or recurrence-free rate (for papillary tumors) of at least 50% at 6 months, 30% at 12 months and 25% at 18 months is recommended.”[1] Based on the 63 patients treated to … Read More
Theralase Release’s 3Q2023 Interim Financial Statements
Toronto, Ontario – November 29th, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses has released the Company’s 3Q2023 unaudited condensed interim consolidated Financial Statements (“Financial Statements”). Financial Summary: For the nine-month period ended September 30th: 1 Other represents foreign exchange, interest accretion on lease liabilities and / or interest income Financial Highlights for the Nine-Month Period Ended September 30th, 2023: Total revenue decreased 13%, year over year. Cost of sales for the nine-month period ended September 30th, 2023 was $363,882 or 51% of revenue resulting in a gross margin of $342,813 or 49% of revenue. In comparison, the cost of sales for the same period in 2022 was $389,232 or 48% of revenue resulting … Read More
Theralase® Closes $CAN 1.17 Million Non-Brokered Private Placement
November 29, 2023, Theralase® successfully closed a non-brokered private placement offering of units for gross proceeds of approximately $CAN 1,170,000.
Theralase® Commences Non-Brokered Private Placement and Termination of Previously Announced Financing
Toronto, Ontario – November 17, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) used for the safe and effective destruction of various cancers, bacteria and viruses, has commenced a non-brokered private placement of units of the Company (“Units”) to raise up to $CAN 1.5 M (“Offering”). In the Offering, each Unit is priced at $CAN 0.22 and consists of one common share of the Company (“Common Share”) and one Common Share purchase warrant (“Warrant”). Each Warrant will entitle the holder thereof to purchase one Common Share of the Company (“Warrant Share“) for a period of 60 months following the Closing Date (as defined herein) of the Offering at an exercise price of $CAN 0.28 per Warrant Share. The Company plans to use the proceeds of the Offering to further the Phase II Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study currently underway … Read More
Theralase® Announces Brokered LIFE Financing
Toronto, Ontario – October 23, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses. Theralase® is pleased to announce that it has entered into an agreement with Research Capital Corporation as the sole agent and sole bookrunner (“RCC” or “Agent”) on a “best efforts” agency basis, brokered offering (“Offering”) of units of the Company (“Units”) at a price of C$0.22 per Unit. The Offering will be subject to a minimum of 15,909,091 Units and a maximum of 24,090,910 Units at a price of C$0.22 per Unit for aggregate gross proceeds to the Company of a minimum C$3,500,000 and up to a maximum of C$5,300,000. Each Unit consists of one (1) common share of the Company (“Common Share”) and one (1) Common Share purchase warrant (“Warrant”). Each Warrant will entitle … Read More
Theralase® Provides Update on Bladder Cancer Clinical Study
Theralase®’s Latest Clinical Data Demonstrates 65% of Patients Treated with Theralase®’s Anti-Cancer Therapy Achieved a Complete Response Toronto, Ontario – October 16, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF) is a clinical stage pharmaceutical company dedicated to the research and development of light or radiation activated Photo Dynamic Compounds (“PDCs”) for the safe and effective destruction of various cancers, bacteria and viruses. Theralase® is providing an update to its Phase II Bacillus Calmette Guérin (“BCG”)-Unresponsive Non-Muscle Invasive Bladder Cancer (“NMIBC”) Carcinoma In-Situ (“CIS”) (with or without resected Ta / T1 papillary disease) clinical study (“Study II”). To date, Theralase® has enrolled and provided the primary Study II Treatment for 62 patients. The Study II Endpoints have been defined as: Primary: Efficacy – Defined as Complete Response (“CR”) rate at any point in time (CR is defined as at least one of the following: Secondary: Duration of CR – Defined as 12 months post initial CR assessment Tertiary: Safety … Read More
Theralase® Demonstrates 8 Year Shelf Life of Lead Drug Ruvidar™
Toronto, Ontario – September 29, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF) is a clinical stage pharmaceutical company that is dedicated to the research and development of light and radiation activated Photo Dynamic Compounds (“PDCs”), their associated drug formulations and the light systems that activate them. These PDCs are intended to safely and effectively destroy various cancers, bacteria and viruses, when light or radiation activated. Supported by current Good Manufacturing Practice (“cGMP”) analysis conducted by an independent manufacturing and testing laboratory, Theralase® announced that it has successfully demonstrated an 8 year, real-time, shelf life of its lead PDC, RuvidarTM. Dr. Arkady Mandel, MD, PhD, DSc, Chief Scientific Officer of Theralase® stated, “Theralase®’s ability to demonstrate such an extended shelf life of its lead PDC, RuvidarTM is extremely encouraging, as it supports our ongoing clinical development plans. This independent analysis confirms the ability of RuvidarTM to be an extremely stable small molecule that has the … Read More
Theralase® Successfully Completes Non-GLP Toxicity Analysis for Brain Cancer
Toronto, Ontario – September 27, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF) is a clinical stage pharmaceutical company that is dedicated to the research and development of light and radiation activated Photo Dynamic Compounds (“PDCs”), their associated drug formulations and the light systems that activate them. These PDCs are intended to safely and effectively destroy various cancers, bacteria and viruses when light or radiation activated. Theralase® announced that it has successfully completed its non-Good Laboratory Practices (“GLP”) preclinical toxicology analysis of Rutherrin® for Glio Blastoma Multiforme (“GBM”). GBM is the most aggressive and most common type of brain cancer. The preclinical toxicology data collected to date has demonstrated that Theralase®’s Rutherrin® (RuvidarTM + human transferrin) PDC is able to be safely administered Intra Venously (“IV”) into brain cancer animal models and then successfully hunt, target and significantly accumulate inside GBM cells versus healthy brain cells. When the PDC is activated by radiation … Read More
Theralase® Grants Stock Options
Toronto, Ontario – September 21, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”), their associated drug formulations and the light systems that activate them, intended to safely and effectively destroy various cancers, announces the grant of stock options. The Company has granted an aggregate of 360,000 stock options to certain directors and employees pursuant to the Company’s stock option plan. The options granted, are exercisable at a price of $CAN 0.25 per share that vest over a three-year period and expire five years from the date of the grant. The stock option plan was last approved by the shareholders of the Company at the Annual General and Special Meeting of Shareholders held on June 29, 2023. About Theralase® Technologies Inc.: Theralase® is a clinical stage pharmaceutical company dedicated to the research and development of light and radiation … Read More
Theralase Release’s 2Q2023 Interim Financial Statements
Toronto, Ontario – August 29th, 2023, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light activated Photo Dynamic Compounds (“PDCs”), their associated drug formulations and the light systems that activate them, intended to safely and effectively destroy various cancers has released the Company’s 2Q2023 unaudited condensed interim consolidated Financial Statements (“Financial Statements”). Financial Summary: For the six-month period ended June 30th: Audited Consolidated Statements of Operations(In Canadian Dollars) 2023 2022 % Change Revenue Canada 305,666 426,990 -28% United States 120,421 125,452 -4% Total Revenue 426,087 552,442 -23% Cost of Sales 224,947 271,656 -17% Gross Margin 201,140 280,786 -28% Gross Margin (% of revenue) 47% 51% Operating Expenses Selling Expenses 147,304 167,139 -12% Administrative Expenses 1,010,144 734,081 38% Research and Development Expenses – Device Division 25,163 105,353 -76% … Read More