Toronto, Ontario – January 18, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TLT: TSXV) (TLTFF: OTC), a leading biotech company focused on the commercialization of medical devices to eliminate pain and when used in conjunction with Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that the fifth patient in a Phase Ib Non-Muscle Invasive Bladder (“NMIBC”) clinical study (“Study”) was enrolled and treated on January 10, 2018, using the Company’s anti-cancer Photo Dynamic Therapy (“PDT”) technology. The anti-cancer PDT treatment procedure involves the instillation of a water based solution of Theralase’s lead anti-cancer PDC, TLD-1433, through the urethra into the bladder of the patient, to allow the PDC to be preferentially absorbed by NMIBC tumours. The bladder is then drained of the solution, flushed with sterile water to remove non-absorbed solution and refilled with sterile water via a cystoscope. A fibre optic assembly, known as a Dosimetry Fibre … Read More

Toronto, Ontario – January 17, 2018 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced an optimization to the delivery schedule of its proprietary anti-cancer vaccine, increasing its efficacy in the destruction of brain cancer. The anti-cancer vaccine was evaluated in a rat glioma (“RG2”) animal model, an established model of Glioblastoma Multiforme (“GBM”), a deadly form of human brain cancer. As originally disclosed, the anti-cancer vaccine was created by exposing RG2 cells to patented stressors extracorporeally (outside the body) and then injecting this anti-cancer vaccine into rats to delay the progression of brain glioma tumours. The previous data obtained in this model demonstrated an increase of 35% in the survival of animals that have been vaccinated twice versus control (non-vaccinated rats). In the latest research, rats were vaccinated twice and then … Read More

Toronto, Ontario – November 30, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has discovered that its Theralase® Cold Laser Therapy (“Theralase® CLT”) has been proven effective, preclinically, to enhance cancer cell destruction by standard cancer treatments. It was previously disclosed that one of the hallmarks of cancer cells is a change in cellular metabolism from an oxygenated process (mitochondrial respiration through the production of Adenosine Triphosphate (“ATP”) that relies on oxygen consumption) to an non-oxygenated process (glycolysis, an oxygen independent process), known as the “Warburg Effect”. Cancer cells modify their cellular metabolism to ensure their survival and proliferation, thus making them difficult to destroy by standard cancer treatments. Theralase has demonstrated, in previous research, preclinically, that its Theralase® CLT, using … Read More

Toronto, Ontario – November 29, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical devices to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that for the nine-month period ended September 30, 2017, total revenue increased to $1,354,254 from $1,206,726 for the same period in 2016, a 12% increase. In Canada, revenue increased 44% to $1,046,508 for the nine-month period ended September 30, 2017 from $728,277 for the nine-month period ended September 30, 2016. In the US, revenue decreased 32% to $272,305 from $399,445 and international revenue decreased 55% to $35,441 from $79,004 for the same periods. The increase in Canadian revenue in 2017 and the corresponding decrease in US and international revenue is attributable to the Company systematically building its sales and marketing teams commencing with the Canadian market, … Read More

Toronto, Ontario – November 27, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced that its Theralase® therapeutic laser technology platform has been proven preclinically to render cancer cells more susceptible to cancer destruction by Photo Dynamic Therapy (“PDT”), by reversing the Warburg Effect. One of the hallmarks of cancer cells is a change in cellular metabolism from mitochondrial respiration (the production of Adenosine TriPhosphate (“ATP”)) that relies on oxygen consumption to glycolysis, an oxygen independent process. Cancer cells systematically modify their metabolism to promote their: growth, survival, proliferation and long-term maintenance, without the need for molecular oxygen, thus making them difficult to destroy by traditional means. This common feature, amongst cancer cells, of a modified metabolism, is demonstrated by … Read More

Toronto, Ontario – November 22, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced that it has validated its new anti-cancer vaccine in an additional animal cancer model for colorectal cancer. The new anti-cancer vaccine was validated in a subcutaneous, colorectal cancer cell (CT.26 WT) mouse model, demonstrating that Theralase’s new anti-cancer vaccine is not solely limited to GlioBlastoma Multiforme (“GBM”) brain cancer cells (previously validated in a Rat Glioma (“RG2”) model), but is also able to be adapted to other types of cancer cell lines, in which the animal’s immune system is stimulated and subsequently programmed to hunt, recognize and destroy cancer cells of specific types. In Theralase conducted research, it was demonstrated that the new anti-cancer vaccine was able … Read More

Toronto, Ontario – November 21, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical devices to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer, announced today that it has demonstrated 24 months long term stability of a second clinical batch of its lead anti-cancer PDC, TLD-1433. The confirmation of 24 months long term stability of the second clinical batch of TLD-1433 ensures that sufficient amount of the PDC will be available at Good Manufacturing Practice (“GMP”) levels for multiple Photo Dynamic Therapy (“PDT”) patient treatments during the planned Phase 2 clinical study for Non-Muscle Invasive Bladder Cancer (“NMIBC”). Stability studies are an essential component of pharmaceutical development, allowing evaluation of a drug’s stability under the influence of a variety of environmental factors such as: temperature, humidity and light. Data from these studies … Read More

Toronto, Ontario – November 20, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has announced the discovery of a new anti-cancer vaccine. This new anti-cancer vaccine was created by exposing Rat Glioma (RG2) cancer cells, representative of GlioBlastoma Multiforme (“GBM”), a deadly form of human brain cancer, to proprietary and patented stressors extracorporeally (outside the body) and then injecting this anti-cancer vaccine into rats to delay the progression of brain gliomas, utilizing a well-established animal model of GBM. The data obtained in this model by Theralase researchers demonstrated a significant increase of 35% in the survival of animals versus control (no vaccination). In previous research, Theralase reported that Rutherrin® (TLD-1433 + transferrin) injected intravenously (“IV”) into an animal diagnosed with GBM was able to effectively cross the Blood Brain Barrier (“BBB”) and localize preferentially to … Read More

Toronto, Ontario – November 13, 2017 Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer has recently identified a new platform of super potent anti-cancer drugs, or PDCs, discovered by Dr. Sherri McFarland, Ph.D., Professor, Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, the original inventor of the Theralase licenced ruthenium-based PDCs. Dr. McFarland has discovered a new generation of PDCs, that are 10 billion times more potent in killing cancer cells than other tested PDCs. It only takes a few molecules of the new PDCs to kill cancer cells, in vitro, when activated by visible light. The new PDCs also exhibit very low, in vitro, dark cytotoxicity (cancer cell kill in the absence of light), providing a very low … Read More

Toronto, Ontario – November 8, 2017 First Four Patients Treated with Company’s Anti-Cancer Treatment Achieve Pre-Defined Primary, Secondary and Exploratory Outcome Measures Theralase Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQX: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds (“PDCs”) to destroy cancer provides an interim data analysis on the first four patients treated, with the Company’s patented, light-activated PDC, TLD-1433, in a Phase Ib Non-Muscle Invasive Bladder Cancer (“NMIBC”) clinical study (“Study”), demonstrating successful achievement of the pre-defined primary, secondary and exploratory outcome measures. The Study entitled, “A Phase Ib Trial of Intravesical Photo Dynamic Therapy (“PDT”) in Patients with NMIBC at High Risk of Progression, Who are Refractory to Therapy with Bacillus Calmette-Guerin (“BCG”) and Who are Medically Unfit for or Refuse a Cystectomy” commenced treating patients in March 2017 and to date … Read More