Rutherrin® Increases Efficacy of Chemotherapy for Lung Cancer

V.TLT |August 28, 2024 Toronto, Ontario – Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light, radiation and or drug-activated small molecules and their formulations, intended for the safe and effective destruction of various cancers, bacteria and viruses, is pleased to announce that it’s lead drug formulation, Rutherrin®, has demonstrated an ability to provide a significant enhancement of Cisplatin efficacy in chemotherapy resistant Non-Small Cell Lung Cancer (“NSCLC”) in a preclinical animal model. Theralase® recently press released its latest research, using the well-established Lewis Lung Cancer (“LLC1”) orthotopic model, representing NSCLC. In this model, mouse lungs are implanted with lung cancer cells, inducing these mice to develop very aggressive, fast growing and metastatic lung tumors. In further experimentation, mice were treated with Cisplatin (currently one of the most prescribed chemotherapy drugs for lung cancer) in a … Read More

Theralase® Demonstrates Unique Ability to Activate Rutherrin® with Diabetes Drug

Toronto, Ontario –August 21 2024, Theralase® Technologies Inc. (“Theralase®” or the “Company”) (TSXV: TLT) (OTCQB: TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation-activated small molecules for the safe and effective destruction of various cancers, bacteria and viruses, is pleased to announce that it’s lead drug formulation, Rutherrin® has been proven preclinically to be activated by Metformin, a common diabetes drug, without the use of light and/or radiation. Even more interesting is that because Rutherrin® and Metformin are both scientifically proven to cross the blood-brain barrier, as well as tumour-specific blood barriers, this new discovery potentially allows the precise targeting of cancer cells by Rutherrin® anywhere inside the body, including the brain, followed by their synergistic activation by Metformin. Metformin, an anti-diabetic agent, was approved by the U.S. Food and Drug Administration in 1994 for the treatment of Type 2 diabetes (a medical condition … Read More

Ruvidar Enhances Efficacy of Cancer Drug

June 10, 2024 – Ruvidar™, in combination with Bacillus Calmette-Guérin (BCG), significantly enhances the cancer cell-killing efficacy compared to BCG or Ruvidar™ alone, even without light activation.