Much of the safety and effectiveness of cold laser therapy lies in its ability to trigger the body to heal itself. Penetrating into targeted tissue, laser light stimulates mitochondria in target cells to produce additional ATP, which fuels cell repair and regeneration. The laser simply jumpstarts the healing process and since the laser used operates within a specific wavelength range that is non thermal (the "therapeutic window"), there is no risk of tissue damage or other complications.
A wide variety of studies on the safety and effectiveness of cold laser therapy have been conducted by medical professionals from across the globe. Theralase® also regularly conducts research and clinical trials to support the use of and discover new applications for laser technology.
TLC-2000 delivers energy deep into tissue (up to 5")
Cellular Pathway Activation
Theralase® utilizes dual wavelength super pulsing technology (660 nm visible red laser diodes and 905 nm super-pulsed near infrared laser diodes) to be the only laser known to activate all three known cellular pathways simultaneously. Light from laser penetrates into tissue, where light energy is converted into chemical or physical energy.
Theralase® laser technology effectively removes the pain signal at source by rebalancing the sodium potassium pathway. (Harvard Medical School, 2010)
Independent research proves that the proprietary Theralase® 905nm superpulsed laser technology increases the production of Nitric Oxide (NO) by over 700%, increasing vasodilation and decreasing inflammation versus other competitive wavelengths. (Lasers in Surgery and Medicine, 2009)
Theralase® stimulates the mitochondria of the cell to produce more Adenosine Triphosphate (ATP or basic cell energy) to accelerate tissue repair. (Proceedings of the International Society for Optics and Photonics, 2015)
Peak Activation By 905 nm, Near Infrared Red Light
Pain results when a stimulus causes action potentials to rapidly propagate along a nerve cell. These actions potentials are primarily due to an expulsion of positively charged sodium ions (Na+) and an influx of potassium (K+) ions into the nerve cell altering the electrical potential across the membrane. The peak absorption of lipids is in the 905 nm to 910 nm range. Laser light is thus directly absorbed by receptors within the bi-lipid cellular membrane of nerve cells. Once absorbed, the laser light will increase the porosity of the cellular membrane allowing for a reabsorption of sodium ions and expulsion of potassium ions across the cellular membrane rebalancing the sodium-potassium pump and removing the pain signal at source.
Lipid Absorption Pathway
Activated By 905 nm, Near Infrared Red Light
When tissue injury occurs, the inflammatory process is initiated to immobilize the area to prevent further damage, providing us with an indication that the body is hurt. This process is usually associated with pain caused by inflammation pressuring nerve endings. In order to reabsorb this interstitial fluid and decrease inflammation in the region, the body produces nitric oxide (NO), which has been proven to relax the lymphatic system causing it to become more porous allowing the reabsorption process to occur. This process not only reduces inflammation but causes temporary vasodilation (increased diameter of capillaries) bringing much needed oxygen, fuel molecules and other metabolites to the injured tissue aiding in their natural healing.
Nitric Oxide (NO) Pathway
630 to 670 nm – Visible Red Light peaking at 660 nm
Cells that lack energy are unable to participate in the healing process. Light energy is delivered to injured cells which in turn absorbs the light and converts it into food energy and uses it to replenish themselves. Once cells are fully recharged they are able to replicate and divide, and build upon one another to heal the injured area. Theralase® stimulates the mitochondria of the cell to produce more ATP (energy) thus repairing damaged tissue through the phosphorylation of glucose to ATP via the Kreb's Cycle and Electron Transport Chain. Photons with wavelengths between 630nm - 670nm increase the speed at which the mitchondria can absorb glucose and convert it into ATP. Theralase® uses 660 nm visible red laser light, which is at the peak excitation of cytochrome C oxidase (a critical cytochome in the Electron Transport Chain used in the phosphorylation of glucose into ATP)