The Photo Dynamic Therapy division focuses on the discovery of small, light-activated molecules and the development of laser systems that target and destroy cancer cells, control bacterial infections, and promote microbial sterilization. Photo Dynamic Compounds (PDCs) are drugs that are cytotoxic (cell killing) when exposed to light at specific wavelengths and power levels. Theralase® photo dynamic compounds can be activated by a wide range of laser wavelengths and function effectively regardless of the oxygenation level present in the tissue under treatment, a unique and advantageous feature when dealing with cancerous tissue and certain bacteria that thrive in low oxygenated tissues. Theralase® has partnered with the world-renowned Princess Margaret Cancer Centre in Toronto, Canada on a Phase 1B clinical trial of Non-Muscle Invasive Bladder Cancer using our lead photo dynamic compound.
Theralase’s TLD-1433 photo dynamic compound has proven to be highly toxic to bladder cancer cells when activated by light, producing a 100% kill rate at very low concentrations.
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